KEGG   REACTION: R00421
Entry
R00421                      Reaction                               
Name
UDP-N-acetyl-D-glucosamine:NAD+ 6-oxidoreductase
Definition
UDP-N-acetyl-alpha-D-glucosamine + 2 NAD+ + H2O <=> UDP-N-acetyl-2-amino-2-deoxy-D-glucuronate + 2 NADH + 2 H+
Equation
C00043 + 2 C00003 + C00001 <=> C04573 + 2 C00004 + 2 C00080
Reaction class
RC00001  C00003_C00004
RC00291  C00043_C04573
Enzyme
1.1.1.136
Pathway
rn00541  Biosynthesis of various nucleotide sugars
rn01100  Metabolic pathways
rn01250  Biosynthesis of nucleotide sugars
Module
M01005  UDP-XylNAc biosynthesis, UDP-GlcNAc => UDP-XylNAc
M01035  UDP-ManNAc3NAcA biosynthesis, UDP-GlcNAc => UDP-ManNAc3NAcA
M01036  UDP-GalNAcA biosynthesis, UDP-GlcNAc => UDP-GalNAcA
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.136
     R00421  UDP-N-acetyl-alpha-D-glucosamine + 2 NAD+ + H2O <=> UDP-N-acetyl-2-amino-2-deoxy-D-glucuronate + 2 NADH + 2 H+
Orthology
K02474  UDP-N-acetyl-D-glucosamine/UDP-N-acetyl-D-galactosamine dehydrogenase [EC:1.1.1.136 1.1.1.-]
K13015  UDP-N-acetyl-D-glucosamine dehydrogenase [EC:1.1.1.136]
K22926  UDP-N-acetylglucosamine 6-dehydrogenase [EC:1.1.1.136]
Other DBs
RHEA: 13328

  All links  
Chemical reaction (1)   
   SABIO-RK (1)   
All databases (1)   

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