KEGG   REACTION: R00702
Entry
R00702                      Reaction                               
Name
farnesyl-diphosphate:farnesyl-diphosphate farnesyltransferase
Definition
2 trans,trans-Farnesyl diphosphate <=> Diphosphate + Presqualene diphosphate
Equation
2 C00448 <=> C00013 + C03428
Comment
the first step of two-step reaction (R06223, R00702+R02872)
the first step of two-step reaction (R07652, R00702+R09793)
Reaction class
RC00362  C00448_C03428
Enzyme
2.5.1.21        2.5.1.96        2.5.1.103
Pathway
rn00100  Steroid biosynthesis
rn00906  Carotenoid biosynthesis
rn00909  Sesquiterpenoid and triterpenoid biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00101  Cholesterol biosynthesis, FPP => cholesterol
M00102  Ergocalciferol biosynthesis, FPP => ergosterol/ergocalciferol
M01038  Staphyloxanthin biosynthesis, bacteria, farnesyl-PP => staphyloxanthin
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.21
     R00702  2 trans,trans-Farnesyl diphosphate <=> Diphosphate + Presqualene diphosphate
    2.5.1.96
     R00702  2 trans,trans-Farnesyl diphosphate <=> Diphosphate + Presqualene diphosphate
    2.5.1.103
     R00702  2 trans,trans-Farnesyl diphosphate <=> Diphosphate + Presqualene diphosphate
Orthology
K00801  farnesyl-diphosphate farnesyltransferase [EC:2.5.1.21]
K10208  4,4'-diapophytoene synthase [EC:2.5.1.96]
Other DBs
RHEA: 22675

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