KEGG   REACTION: R00709Help
Entry
R00709                      Reaction                               

Name
isocitrate:NAD+ oxidoreductase (decarboxylating)
Definition
Isocitrate + NAD+ <=> 2-Oxoglutarate + CO2 + NADH + H+
Equation
Reaction class
RC00001  C00003_C00004
RC00114  C00026_C00311
RC02801  C00011_C00311
Enzyme
1.1.1.41        1.1.1.286
Pathway
rn00020  Citrate cycle (TCA cycle)
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01200  Carbon metabolism
rn01210  2-Oxocarboxylic acid metabolism
rn01230  Biosynthesis of amino acids
Module
M00009  Citrate cycle (TCA cycle, Krebs cycle)
M00010  Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Orthology
K00030  isocitrate dehydrogenase (NAD+) [EC:1.1.1.41]
K17753  isocitrate--homoisocitrate dehydrogenase [EC:1.1.1.286]
Other DBs
RHEA: 23635

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