KEGG   REACTION: R00742
Entry
R00742                      Reaction                               
Name
acetyl-CoA:carbon-dioxide ligase (ADP-forming)
Definition
ATP + Acetyl-CoA + HCO3- <=> ADP + Orthophosphate + Malonyl-CoA
Equation
C00002 + C00024 + C00288 <=> C00008 + C00009 + C00083
Comment
two-step reaction (see R04385 + R04386)
Reaction class
RC00002  C00002_C00008
RC00040  C00024_C00083
RC00367  C00083_C00288
Enzyme
6.4.1.2
Pathway
rn00061  Fatty acid biosynthesis
rn00254  Aflatoxin biosynthesis
rn00620  Pyruvate metabolism
rn00640  Propanoate metabolism
rn00720  Carbon fixation pathways in prokaryotes
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01200  Carbon metabolism
rn01212  Fatty acid metabolism
Module
M00082  Fatty acid biosynthesis, initiation
M00375  Hydroxypropionate-hydroxybutylate cycle
M00376  3-Hydroxypropionate bi-cycle
Brite
Enzymatic reactions [BR:br08201]
 6. Ligase reactions
  6.4  Forming carbon-carbon bonds
   6.4.1  Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
    6.4.1.2
     R00742  ATP + Acetyl-CoA + HCO3- <=> ADP + Orthophosphate + Malonyl-CoA
Overall reaction [br08210.html]
 Carbon fixation
  R00742
Orthology
K01946  acetyl-CoA carboxylase / biotin carboxylase 2 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
K01961  acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]
K01962  acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]
K01963  acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15]
K01964  acetyl-CoA/propionyl-CoA carboxylase [EC:6.4.1.2 6.4.1.3]
K02160  acetyl-CoA carboxylase biotin carboxyl carrier protein
K11262  acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
K11263  acetyl-CoA/propionyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein [EC:6.4.1.2 6.4.1.3 6.3.4.14]
K15036  acetyl-CoA/propionyl-CoA carboxylase [EC:6.4.1.2 6.4.1.3 2.1.3.15]
K15037  biotin carboxyl carrier protein
K18472  acetyl-CoA/propionyl-CoA carboxylase carboxyl transferase subunit [EC:6.4.1.2 6.4.1.3 2.1.3.15]
K18603  acetyl-CoA/propionyl-CoA carboxylase [EC:6.4.1.2 6.4.1.3]
K18604  acetyl-CoA/propionyl-CoA carboxylase [EC:6.4.1.2 6.4.1.3 2.1.3.15]
K18605  biotin carboxyl carrier protein
K19312  acetyl-CoA/propionyl-CoA carboxylase carboxyl transferase subunit [EC:6.4.1.2 6.4.1.3 2.1.3.15]
K22568  acetyl-CoA/propionyl-CoA carboxylase, PccX subunit [EC:6.4.1.2 6.4.1.3]
Other DBs
RHEA: 11311

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Pathway (23)   
   KEGG PATHWAY (20)   
   KEGG MODULE (3)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (5)   
   KEGG ENZYME (1)   
   KEGG RCLASS (3)   
   SABIO-RK (1)   
Gene (32855)   
   KEGG ORTHOLOGY (16)   
   KEGG GENES (32839)   
All databases (32890)   

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