KEGG   REACTION: R00823
Entry
R00823                      Reaction                               
Name
anthranilate,NADH:oxygen oxidoreductase (1,2-hydroxylating, deaminating, decarboxylating)
Definition
Anthranilate + Oxygen + NADH + H+ <=> Catechol + Ammonia + CO2 + NAD+
Equation
C00108 + C00007 + C00004 + C00080 <=> C00090 + C00014 + C00011 + C00003
Comment
NADPH (see R00825)
Reaction class
RC00001  C00003_C00004
RC00192  C00090_C00108
Enzyme
1.14.12.1
Pathway
rn00627  Aminobenzoate degradation
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
Module
M00637  Anthranilate degradation, anthranilate => catechol
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.12  With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor
    1.14.12.1
     R00823  Anthranilate + Oxygen + NADH + H+ <=> Catechol + Ammonia + CO2 + NAD+
Orthology
K05599  anthranilate 1,2-dioxygenase (deaminating, decarboxylating) large subunit [EC:1.14.12.1]
K05600  anthranilate 1,2-dioxygenase (deaminating, decarboxylating) small subunit [EC:1.14.12.1]
K11311  anthranilate 1,2-dioxygenase reductase component [EC:1.18.1.-]
K16319  anthranilate 1,2-dioxygenase large subunit [EC:1.14.12.1]
K16320  anthranilate 1,2-dioxygenase small subunit [EC:1.14.12.1]
K18248  anthranilate 1,2-dioxygenase ferredoxin component
K18249  anthranilate 1,2-dioxygenase ferredoxin reductase component [EC:1.18.1.-]
Reference
1  [PMID:11114907]
  Authors
Eby DM, Beharry ZM, Coulter ED, Kurtz DM Jr, Neidle EL
  Title
Characterization and evolution of anthranilate 1,2-dioxygenase from Acinetobacter sp. strain ADP1.
  Journal
J Bacteriol 183:109-18 (2001)
DOI:10.1128/JB.183-1.109-118.2001
Other DBs
RHEA: 11079

  All links  
Chemical reaction (1)   
   UMBBD-RN (1)   
All databases (1)   

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