KEGG   REACTION: R00942
Entry
R00942                      Reaction                               
Name
tetrahydrofolate:L-glutamate gamma-ligase (ADP-forming)
Definition
ATP + Tetrahydrofolate + L-Glutamate <=> ADP + Orthophosphate + THF-L-glutamate
Equation
C00002 + C00101 + C00025 <=> C00008 + C00009 + C09332
Reaction class
RC00002  C00002_C00008
RC00064  C00025_C09332
RC00090  C00101_C09332
Enzyme
6.3.2.17
Pathway
rn00790  Folate biosynthesis
rn01240  Biosynthesis of cofactors
Brite
Enzymatic reactions [BR:br08201]
 6. Ligase reactions
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.17
     R00942  ATP + Tetrahydrofolate + L-Glutamate <=> ADP + Orthophosphate + THF-L-glutamate
IUBMB reaction hierarchy [BR:br08202]
 6. Ligase reactions
  6.3.2.17
   R04241  THF-polyglutamate <=> THF-polyglutamate
    R00942  Tetrahydrofolate <=> THF-L-glutamate
Orthology
K01930  folylpolyglutamate synthase [EC:6.3.2.17]
K11754  dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]
K22099  dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG RCLASS (3)   
Gene (9909)   
   KEGG ORTHOLOGY (3)   
   KEGG GENES (9906)   
All databases (9925)   

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