KEGG   REACTION: R01078
Entry
R01078                      Reaction                               
Name
dethiobiotin:sulfur sulfurtransferase
Definition
Dethiobiotin + Sulfur donor + 2 S-Adenosyl-L-methionine + 2 e- + 2 H+ <=> Biotin + 2 L-Methionine + 2 5'-Deoxyadenosine
Equation
C01909 + C17023 + 2 C00019 + 2 C05359 + 2 C00080 <=> C00120 + 2 C00073 + 2 C05198
Comment
the reactant sulfur is not elemental sulfur, but it may be from the enzyme itself ([2Fe-2S] iron-sulfur centre)
multi-step reaction
Reaction class
RC00021  C00019_C00073
RC00441  C00120_C01909
Enzyme
2.8.1.6
Pathway
rn00780  Biotin metabolism
rn01100  Metabolic pathways
rn01240  Biosynthesis of cofactors
Module
M00123  Biotin biosynthesis, pimeloyl-ACP/CoA => biotin
M00573  Biotin biosynthesis, BioI pathway, long-chain-acyl-ACP => pimeloyl-ACP => biotin
M00577  Biotin biosynthesis, BioW pathway, pimelate => pimeloyl-CoA => biotin
M00950  Biotin biosynthesis, BioU pathway, pimeloyl-ACP/CoA => biotin
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.8  Transferring sulfur-containing groups
   2.8.1  Sulfurtransferases
    2.8.1.6
     R01078  Dethiobiotin + Sulfur donor + 2 S-Adenosyl-L-methionine + 2 e- + 2 H+ <=> Biotin + 2 L-Methionine + 2 5'-Deoxyadenosine
Orthology
K01012  biotin synthase [EC:2.8.1.6]
Other DBs
RHEA: 22063

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Ontology (1)   
   KEGG BRITE (1)   
Pathway (10)   
   KEGG PATHWAY (6)   
   KEGG MODULE (4)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG RCLASS (2)   
Gene (7499)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (7498)   
All databases (7521)   

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