KEGG   REACTION: R01088
Entry
R01088                      Reaction                               
Name
L-leucine:NAD+ oxidoreductase (deaminating)
Definition
L-Leucine + H2O + NAD+ <=> 4-Methyl-2-oxopentanoate + Ammonia + NADH + H+
Equation
C00123 + C00001 + C00003 <=> C00233 + C00014 + C00004 + C00080
Reaction class
RC00001  C00003_C00004
RC00006  C00123_C00233
Enzyme
1.4.1.9
Pathway
rn00280  Valine, leucine and isoleucine degradation
rn00290  Valine, leucine and isoleucine biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.4  Acting on the CH-NH2 group of donors
   1.4.1  With NAD+ or NADP+ as acceptor
    1.4.1.9
     R01088  L-Leucine + H2O + NAD+ <=> 4-Methyl-2-oxopentanoate + Ammonia + NADH + H+
Orthology
K00263  leucine dehydrogenase [EC:1.4.1.9]
Other DBs
RHEA: 12223

  All links  
Chemical reaction (1)   
   SABIO-RK (1)   
All databases (1)   

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