KEGG   REACTION: R01221Help
Entry
R01221                      Reaction                               

Name
glycine synthase;
glycine cleavage system
Definition
Glycine + Tetrahydrofolate + NAD+ <=> 5,10-Methylenetetrahydrofolate + Ammonia + CO2 + NADH + H+
Equation
Comment
multienzyme system
multi-step reaction (see R03425+R04125+R03815)
Reaction class
RC00001  C00003_C00004
RC00022  C00101_C00143
RC02834  C00014_C00037
Enzyme
1.4.4.2         1.8.1.4         2.1.2.10
Pathway
rn00630  Glyoxylate and dicarboxylate metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01130  Biosynthesis of antibiotics
rn01200  Carbon metabolism
Module
M00532  Photorespiration
Orthology
K00281  glycine dehydrogenase [EC:1.4.4.2]
K00282  glycine dehydrogenase subunit 1 [EC:1.4.4.2]
K00283  glycine dehydrogenase subunit 2 [EC:1.4.4.2]
K00382  dihydrolipoamide dehydrogenase [EC:1.8.1.4]
K00605  aminomethyltransferase [EC:2.1.2.10]
K02437  glycine cleavage system H protein
Other DBs
RHEA: 27761

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