KEGG   REACTION: R01226
Entry
R01226                      Reaction                               

Name
5,10-Methylenetetrahydrofolate:3-methyl-2-oxobutanoate hydroxymethyltransferase
Definition
5,10-Methylenetetrahydrofolate + 3-Methyl-2-oxobutanoic acid + H2O <=> Tetrahydrofolate + 2-Dehydropantoate
Equation
Comment
multi-step reaction
Reaction class
RC00022  C00101_C00143
RC00200  C00141_C00966
Enzyme
Pathway
rn00770  Pantothenate and CoA biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01240  Biosynthesis of cofactors
Module
M00119  Pantothenate biosynthesis, valine/L-aspartate => pantothenate
M00913  Pantothenate biosynthesis, 2-oxoisovalerate/spermine => pantothenate
M00914  Coenzyme A biosynthesis, archaea, 2-oxoisovalerate => 4-phosphopantoate => CoA
Orthology
K00606  3-methyl-2-oxobutanoate hydroxymethyltransferase [EC:2.1.2.11]
Other DBs
RHEA: 11827

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