KEGG   REACTION: R01360Help
Entry
R01360                      Reaction                               

Name
(S)-3-hydroxy-3-methylglutaryl-CoA acetoacetate-lyase (acetyl-CoA-forming)
Definition
(S)-3-Hydroxy-3-methylglutaryl-CoA <=> Acetyl-CoA + Acetoacetate
Equation
Reaction class
RC00502  C00024_C00356
RC00503  C00164_C00356
Enzyme
Pathway
rn00072  Synthesis and degradation of ketone bodies
rn00280  Valine, leucine and isoleucine degradation
rn00650  Butanoate metabolism
rn01100  Metabolic pathways
Module
M00036  Leucine degradation, leucine => acetoacetate + acetyl-CoA
M00088  Ketone body biosynthesis, acetyl-CoA => acetoacetate/3-hydroxybutyrate/acetone
Orthology
K01640  hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4]
Other DBs
RHEA: 24407

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