KEGG   REACTION: R01630
Entry
R01630                      Reaction                               
Name
protocatechuate,NADPH:oxygen oxidoreductase (1-hydroxylating, decarboxylating)
Definition
3,4-Dihydroxybenzoate + Oxygen + NADPH + H+ <=> Benzene-1,2,4-triol + CO2 + NADP+ + H2O
Equation
C00230 + C00007 + C00005 + C00080 <=> C02814 + C00011 + C00006 + C00001
Comment
NADH (see R01629)
Reaction class
RC00001  C00005_C00006
RC00115  C00230_C02814
Enzyme
1.14.13.64
Pathway
rn00362  Benzoate degradation
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.64
     R01630  3,4-Dihydroxybenzoate + Oxygen + NADPH + H+ <=> Benzene-1,2,4-triol + CO2 + NADP+ + H2O
Reference
1  [PMID:9352916]
  Authors
Eppink MH, Boeren SA, Vervoort J, van Berkel WJ.
  Title
Purification and properties of 4-hydroxybenzoate 1-hydroxylase (decarboxylating), a novel flavin adenine dinucleotide-dependent monooxygenase from Candida parapsilosis CBS604.
  Journal
J Bacteriol 179:6680-7 (1997)
DOI:10.1128/JB.179.21.6680-6687.1997
Other DBs
RHEA: 30042

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Ontology (1)   
   KEGG BRITE (1)   
Pathway (6)   
   KEGG PATHWAY (6)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG RCLASS (2)   
All databases (18)   

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