KEGG   REACTION: R01701
Entry
R01701                      Reaction                               
Name
3-methyl-2-oxobutanoate:[dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-2-methylpropanoylating)
Definition
3-Methyl-2-oxobutanoic acid + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylpropanoyl)dihydrolipoyllysine + CO2
Equation
C00141 + C15972 <=> C15977 + C00011
Comment
3-methyl-2-oxobutanoate dehydrogenase complexes:3-methyl-2-oxobutanoate dehydrogenase
a part of multi-step reaction (see R01701+R02662+R07618, possibly identical to R01210)
subsequently R02662
TPP-dependent enzyme (see R07599+R07600)
Reaction class
RC00627  C15972_C15977
RC02856  C00141_C15977
Enzyme
1.2.4.4
Pathway
rn01100  Metabolic pathways
Orthology
K00166  2-oxoisovalerate dehydrogenase E1 component alpha subunit [EC:1.2.4.4]
K00167  2-oxoisovalerate dehydrogenase E1 component beta subunit [EC:1.2.4.4]
K11381  2-oxoisovalerate dehydrogenase E1 component [EC:1.2.4.4]
Other DBs
RHEA: 13460

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Ontology (1)   
   KEGG BRITE (1)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG RCLASS (2)   
Gene (9619)   
   KEGG ORTHOLOGY (3)   
   KEGG GENES (9616)   
All databases (9629)   

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