KEGG   REACTION: R01813Help
Entry
R01813                      Reaction                               

Name
tetrahydrobiopterin:NADP+ oxidoreductase
Definition
Tetrahydrobiopterin + NADP+ <=> 6-Lactoyl-5,6,7,8-tetrahydropterin + NADPH + H+
Equation
Comment
a part of three-step reaction (see R08208, R01813+R11762+R11763)
Reaction class
RC00001  C00005_C00006
RC00602  C00272_C04244
Enzyme
Pathway
rn00790  Folate biosynthesis
rn01100  Metabolic pathways
Orthology
K00072  sepiapterin reductase [EC:1.1.1.153]
Other DBs
RHEA: 42503

KEGG   REACTION: R11762Help
Entry
R11762                      Reaction                               

Definition
6-Lactoyl-5,6,7,8-tetrahydropterin <=> 6-(1'-Hydroxy-2'-oxopropyl)-tetrahydropterin
Equation
Comment
a part of three-step reaction (see R08208, R01813+R11762+R11763)
isomerization
Reaction class
RC03490  C04244_C21640
Enzyme
Orthology
K00072  sepiapterin reductase [EC:1.1.1.153]

KEGG   REACTION: R11763Help
Entry
R11763                      Reaction                               

Name
6-(1'-hydroxy-2'-oxopropyl)-tetrahydropterin:NADP+ oxidoreductase
Definition
6-(1'-Hydroxy-2'-oxopropyl)-tetrahydropterin + NADP+ <=> 6-Pyruvoyltetrahydropterin + NADPH + H+
Equation
Comment
a part of three-step reaction (see R08208, R01813+R11762+R11763)
Reaction class
RC03491  C03684_C21640
Enzyme
1.1.1.153       1.1.1.213
Pathway
rn00790  Folate biosynthesis
rn01100  Metabolic pathways
Orthology
K00072  sepiapterin reductase [EC:1.1.1.153]
K04119  aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357]

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