KEGG   REACTION: R01814Help
Entry
R01814                      Reaction                               

Name
L-Tryptophan,tetrahydrobiopterin:oxygen oxidoreductase (5-hydroxylating)
Definition
Tetrahydrobiopterin + L-Tryptophan + Oxygen <=> 5-Hydroxy-L-tryptophan + Dihydrobiopterin + H2O
Equation
Comment
two-step reaction (see R07213+R04734)
Reaction class
RC00023  C00268_C00272
RC00490  C00078_C00643
Enzyme
Pathway
rn00380  Tryptophan metabolism
rn01100  Metabolic pathways
Module
M00037  Melatonin biosynthesis, tryptophan => serotonin => melatonin
Orthology
K00502  tryptophan 5-monooxygenase [EC:1.14.16.4]

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