KEGG   REACTION: R02236
Entry
R02236                      Reaction                               
Name
dihydrofolate:NADP+ oxidoreductase
Definition
Dihydrofolate + NADP+ <=> Folate + NADPH + H+
Equation
C00415 + C00006 <=> C00504 + C00005 + C00080
Reaction class
RC00001  C00005_C00006
RC00158  C00415_C00504
Enzyme
1.5.1.3
Pathway
rn00670  One carbon pool by folate
rn00790  Folate biosynthesis
rn01100  Metabolic pathways
rn01240  Biosynthesis of cofactors
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3
     R02236  Dihydrofolate + NADP+ <=> Folate + NADPH + H+
Orthology
K00287  dihydrofolate reductase [EC:1.5.1.3]
K13998  dihydrofolate reductase / thymidylate synthase [EC:1.5.1.3 2.1.1.45]
K18589  dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
K18590  dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
K18591  dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
K19643  dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
K19644  dihydrofolate reductase (trimethoprim resistance protein) [EC:1.5.1.3]
Other DBs
RHEA: 31106

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Pathway (8)   
   KEGG PATHWAY (8)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG RCLASS (2)   
   SABIO-RK (1)   
Gene (8684)   
   KEGG ORTHOLOGY (7)   
   KEGG GENES (8677)   
All databases (8702)   

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