KEGG   REACTION: R02253
Entry
R02253                      Reaction                               
Name
trans-cinnamate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (4-hydroxylating)
Definition
trans-Cinnamate + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 4-Coumarate + [Oxidized NADPH---hemoprotein reductase] + H2O
Equation
C00423 + C03024 + C00007 <=> C00811 + C03161 + C00001
Reaction class
RC00490  C00423_C00811
Enzyme
1.14.14.91
Pathway
rn00130  Ubiquinone and other terpenoid-quinone biosynthesis
rn00940  Phenylpropanoid biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01220  Degradation of aromatic compounds
Module
M00039  Monolignol biosynthesis, phenylalanine/tyrosine => monolignol
M00137  Flavanone biosynthesis, phenylalanine => naringenin
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.91
     R02253  trans-Cinnamate + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 4-Coumarate + [Oxidized NADPH---hemoprotein reductase] + H2O
Orthology
K00487  trans-cinnamate 4-monooxygenase [EC:1.14.14.91]
Other DBs
RHEA: 10611

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