REACTION: R02580
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Entry
R02580 Reaction
Name
(5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-13-enoate:NAD+15-oxidoreductase
Definition
Prostaglandin E2 + NAD+ <=> (5Z,13E)-11alpha-Hydroxy-9,15-dioxoprost-5,13-dienoate + NADH + H+
Equation
C00584
+
C00003
<=>
C04707
+
C00004
+
C00080
Reaction class
RC00001
C00003_C00004
RC00241
C00584_C04707
Enzyme
1.1.1.141
Pathway
rn00590
Arachidonic acid metabolism
Brite
Enzymatic reactions [BR:
br08201
]
1. Oxidoreductase reactions
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.141
R02580 Prostaglandin E2 + NAD+ <=> (5Z,13E)-11alpha-Hydroxy-9,15-dioxoprost-5,13-dienoate + NADH + H+
BRITE hierarchy
Orthology
K00069
15-hydroxyprostaglandin dehydrogenase (NAD) [EC:
1.1.1.141
]
Other DBs
RHEA:
11879
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Chemical reaction (1)
SABIO-RK (1)
All databases (1)
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