KEGG   REACTION: R03102
Entry
R03102                      Reaction                               

Name
L-2-aminoadipate-6-semialdehyde:NAD+ 6-oxidoreductase
Definition
L-2-Aminoadipate 6-semialdehyde + NAD+ + H2O <=> L-2-Aminoadipate + NADH + H+
Equation
Comment
NADP+ (see R03103)
two-step reaction (see R02317+R11231)
Reaction class
RC00001  C00003_C00004
RC00080  C00956_C04076
Enzyme
Pathway
rn00310  Lysine degradation
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00032  Lysine degradation, lysine => saccharopine => acetoacetyl-CoA
Orthology
K14085  aldehyde dehydrogenase family 7 member A1 [EC:1.2.1.31 1.2.1.8 1.2.1.3]
Other DBs
RHEA: 12311

KEGG   REACTION: R02317
Entry
R02317                      Reaction                               

Name
(S)-2-amino-6-oxohexanoate hydro-lyase (spontaneous)
Definition
(S)-2,3,4,5-Tetrahydropyridine-2-carboxylate + H2O <=> L-2-Aminoadipate 6-semialdehyde
Equation
Comment
spontaneous
second step of two-step reaction (see R10054, R00446+R02317)
first step of two-step reaction (see R03102, R02317+R11231)
first step of two-step reaction (see R03103, R02317+R11232)
Reaction class
RC00694  C00450_C04076
Enzyme
1.2.1.31        1.4.1.18
Pathway
rn00960  Tropane, piperidine and pyridine alkaloid biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Orthology
K19064  lysine 6-dehydrogenase [EC:1.4.1.18]
Other DBs
RHEA: 25124

KEGG   REACTION: R11231
Entry
R11231                      Reaction                               

Definition
(S)-2,3,4,5-Tetrahydropyridine-2-carboxylate + NAD+ + 2 H2O <=> L-2-Aminoadipate + NADH + H+
Equation
Comment
second step of two-step reaction (see R03102, R02317+R11231)
Reaction class
RC00216  C00450_C00956
Enzyme
Other DBs
RHEA: 49479

DBGET integrated database retrieval system