KEGG   REACTION: R03208
Entry
R03208                      Reaction                               
Definition
2 3,5-Diiodo-L-tyrosine + Hydrogen peroxide <=> Thyroxine + Dehydroalanine + 2 H2O
Equation
2 C01060 + C00027 <=> C01829 + C02218 + 2 C00001
Comment
thyroid peroxidase, TPO
reaction on thyroglobulin [KO:K10809] (see R08523)
Reaction class
RC00878  C01060_C01829
RC01037  C01060_C02218
Enzyme
1.11.1.8
Pathway
rn00350  Tyrosine metabolism
rn01100  Metabolic pathways
Module
M00043  Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.11  Acting on a peroxide as acceptor
   1.11.1  Peroxidases
    1.11.1.8
     R03208  2 3,5-Diiodo-L-tyrosine + Hydrogen peroxide <=> Thyroxine + Dehydroalanine + 2 H2O
Orthology
K00431  thyroid peroxidase [EC:1.11.1.8]

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Ontology (1)   
   KEGG BRITE (1)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG RCLASS (2)   
Gene (541)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (540)   
All databases (555)   

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