KEGG   REACTION: R03435
Entry
R03435                      Reaction                               
Name
1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase
Definition
1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate + H2O <=> D-myo-Inositol 1,4,5-trisphosphate + 1,2-Diacyl-sn-glycerol
Equation
C04637 + C00001 <=> C01245 + C00641
Reaction class
RC00017  C00641_C04637
RC00425  C01245_C04637
Enzyme
3.1.4.11
Pathway
rn00562  Inositol phosphate metabolism
rn01100  Metabolic pathways
Module
M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
Enzymatic reactions [BR:br08201]
 3. Hydrolase reactions
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11
     R03435  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate + H2O <=> D-myo-Inositol 1,4,5-trisphosphate + 1,2-Diacyl-sn-glycerol
Orthology
K01116  phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
K05857  phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
K05859  phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
K05860  phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
K05861  phosphatidylinositol phospholipase C, zeta [EC:3.1.4.11]
K19006  phosphatidylinositol phospholipase C, eta [EC:3.1.4.11]
Other DBs
RHEA: 33182

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG RCLASS (2)   
   SABIO-RK (1)   
Gene (8540)   
   KEGG ORTHOLOGY (7)   
   KEGG GENES (8533)   
All databases (8554)   

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