KEGG   REACTION: R04225
Entry
R04225                      Reaction                               
Name
(S)-3-Methyl-2-oxopentanoate:[dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-2-methylpropanoylating)
Definition
(S)-3-Methyl-2-oxopentanoic acid + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylbutanoyl)dihydrolipoyllysine + CO2
Equation
C00671 + C15972 <=> C15979 + C00011
Comment
3-methyl-2-oxobutanoate dehydrogenase complexes:3-methyl-2-oxobutanoate dehydrogenase
a part of multi-step reaction (see R04225+R03174+R07618, possibly identical to R03171)
subsequently R03174
TPP-dependent enzyme (see R07603+R07604)
Reaction class
RC00627  C15972_C15979
RC02856  C00671_C15979
Enzyme
1.2.4.4
Pathway
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Orthology
K00166  2-oxoisovalerate dehydrogenase E1 component alpha subunit [EC:1.2.4.4]
K00167  2-oxoisovalerate dehydrogenase E1 component beta subunit [EC:1.2.4.4]
K11381  2-oxoisovalerate dehydrogenase E1 component [EC:1.2.4.4]

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Ontology (1)   
   KEGG BRITE (1)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG RCLASS (2)   
Gene (9619)   
   KEGG ORTHOLOGY (3)   
   KEGG GENES (9616)   
All databases (9631)   

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