KEGG   REACTION: R04241
Entry
R04241                      Reaction                               
Name
tetrahydropteroyl-gamma-polyglutamate:L-glutamate gamma-ligase (ADP-forming)
Definition
ATP + THF-polyglutamate(n) + L-Glutamate <=> ADP + Orthophosphate + THF-polyglutamate(n+1)
Equation
C00002 + C03541(n) + C00025 <=> C00008 + C00009 + C03541(n+1)
Reaction class
RC00002  C00002_C00008
RC00064  C00025_C03541
Enzyme
6.3.2.17
Pathway
rn00790  Folate biosynthesis
rn01240  Biosynthesis of cofactors
Brite
Enzymatic reactions [BR:br08201]
 6. Ligase reactions
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.17
     R04241  ATP + THF-polyglutamate(n) + L-Glutamate <=> ADP + Orthophosphate + THF-polyglutamate(n+1)
IUBMB reaction hierarchy [BR:br08202]
 6. Ligase reactions
  6.3.2.17
   R04241  THF-polyglutamate <=> THF-polyglutamate
Orthology
K01930  folylpolyglutamate synthase [EC:6.3.2.17]
K11754  dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]
K22099  dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]
Other DBs
RHEA: 10583

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG RCLASS (2)   
Gene (10250)   
   KEGG ORTHOLOGY (3)   
   KEGG GENES (10247)   
All databases (10264)   

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