KEGG   REACTION: R04263
Entry
R04263                      Reaction                               
Name
7alpha-hydroxycholesterol:NAD+ 3-oxidoreductase
Definition
7alpha-Hydroxycholesterol + NAD+ <=> 7alpha-Hydroxycholest-4-en-3-one + NADH + H+
Equation
C03594 + C00003 <=> C05455 + C00004 + C00080
Comment
NADP+ ( see R04264)
Reaction class
RC00001  C00003_C00004
RC01111  C03594_C05455
Enzyme
1.1.1.181
Pathway
rn00120  Primary bile acid biosynthesis
rn01100  Metabolic pathways
Module
M00104  Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.181
     R04263  7alpha-Hydroxycholesterol + NAD+ <=> 7alpha-Hydroxycholest-4-en-3-one + NADH + H+
IUBMB reaction hierarchy [BR:br08202]
 1. Oxidoreductase reactions
  1.1.1.181
   R04263  7alpha-Hydroxycholesterol <=> 7alpha-Hydroxycholest-4-en-3-one
Orthology
K12408  cholest-5-ene-3beta,7alpha-diol 3beta-dehydrogenase [EC:1.1.1.181]
Other DBs
RHEA: 11899

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG RCLASS (2)   
   SABIO-RK (1)   
Gene (437)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (436)   
All databases (453)   

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