KEGG   REACTION: R04463
Entry
R04463                      Reaction                               
Name
5'-phosphoribosylformylglycinamide:L-glutamine amido-ligase (ADP-forming)
Definition
ATP + 5'-Phosphoribosyl-N-formylglycinamide + L-Glutamine + H2O <=> ADP + Orthophosphate + 2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine + L-Glutamate
Equation
C00002 + C04376 + C00064 + C00001 <=> C00008 + C00009 + C04640 + C00025
Reaction class
RC00002  C00002_C00008
RC00010  C00025_C00064
RC01160  C04376_C04640
Enzyme
6.3.5.3
Pathway
rn00230  Purine metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00048  De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
Enzymatic reactions [BR:br08201]
 6. Ligase reactions
  6.3  Forming carbon-nitrogen bonds
   6.3.5  Carbon-nitrogen ligases with glutamine as amido-N-donor
    6.3.5.3
     R04463  ATP + 5'-Phosphoribosyl-N-formylglycinamide + L-Glutamine + H2O <=> ADP + Orthophosphate + 2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine + L-Glutamate
Orthology
K01952  phosphoribosylformylglycinamidine synthase [EC:6.3.5.3]
K23264  phosphoribosylformylglycinamidine synthase subunit PurS [EC:6.3.5.3]
K23265  phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
K23269  phosphoribosylformylglycinamidine synthase subunit PurL [EC:6.3.5.3]
K23270  phosphoribosylformylglycinamidine synthase subunit PurSL [EC:6.3.5.3]
Other DBs
RHEA: 17132

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG RCLASS (3)   
Gene (16514)   
   KEGG ORTHOLOGY (5)   
   KEGG GENES (16509)   
All databases (16534)   

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