KEGG   REACTION: R04560
Entry
R04560                      Reaction                               
Name
10-formyltetrahydrofolate:5'-phosphoribosyl-5-amino-4-imidazolecarboxamide formyltransferase
Definition
10-Formyltetrahydrofolate + 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide <=> Tetrahydrofolate + 1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
Equation
C00234 + C04677 <=> C00101 + C04734
Reaction class
RC00026  C00101_C00234
RC00263  C04677_C04734
Enzyme
2.1.2.3
Pathway
rn00230  Purine metabolism
rn00670  One carbon pool by folate
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00048  De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.3
     R04560  10-Formyltetrahydrofolate + 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide <=> Tetrahydrofolate + 1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
Orthology
K00602  phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
K01492  phosphoribosylglycinamide/phosphoribosylaminoimidazolecarboxamide formyltransferase [EC:2.1.2.2 2.1.2.3]
Other DBs
RHEA: 22195

  All links  
Chemical reaction (1)   
   SABIO-RK (1)   
All databases (1)   

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