KEGG   REACTION: R04673
Entry
R04673                      Reaction                               
Name
(S)-2-aceto-2-hydroxybutanoate pyruvate-lyase (carboxylating)
Definition
2-Oxobutanoate + 2-(alpha-Hydroxyethyl)thiamine diphosphate <=> (S)-2-Aceto-2-hydroxybutanoate + Thiamin diphosphate
Equation
C00109 + C05125 <=> C06006 + C00068
Comment
TPP-dependent enzymatic reaction (see R08648), following after R00014
Reaction class
RC00027  C00068_C05125
RC01192  C00109_C06006
Enzyme
2.2.1.6
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.2  Transferring aldehyde or ketonic groups
   2.2.1  Transketolases and transaldolases
    2.2.1.6
     R04673  2-Oxobutanoate + 2-(alpha-Hydroxyethyl)thiamine diphosphate <=> (S)-2-Aceto-2-hydroxybutanoate + Thiamin diphosphate
Orthology
K01652  acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
K01653  acetolactate synthase I/III small subunit [EC:2.2.1.6]
K11258  acetolactate synthase II small subunit [EC:2.2.1.6]
Other DBs
RHEA: 33694

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