KEGG   REACTION: R04751
Entry
R04751                      Reaction                               
Name
hexanoyl-CoA:electron-transfer flavoprotein 2,3-oxidoreductase
Definition
Hexanoyl-CoA + FAD <=> trans-Hex-2-enoyl-CoA + FADH2
Equation
Reaction class
RC00052  C05270_C05271
RC00126  C00016_C01352
Enzyme
1.3.3.6         1.3.8.1         1.3.8.5         1.3.8.7         
1.3.8.8         1.3.99.-
Pathway
rn00071  Fatty acid degradation
rn01100  Metabolic pathways
rn01212  Fatty acid metabolism
Module
M00087  beta-Oxidation
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.3  Acting on the CH-CH group of donors
   1.3.3  With oxygen as acceptor
    1.3.3.6
     R04751  Hexanoyl-CoA + FAD <=> trans-Hex-2-enoyl-CoA + FADH2
   1.3.8  With a flavin as acceptor
    1.3.8.1
     R04751  Hexanoyl-CoA + FAD <=> trans-Hex-2-enoyl-CoA + FADH2
    1.3.8.5
     R04751  Hexanoyl-CoA + FAD <=> trans-Hex-2-enoyl-CoA + FADH2
    1.3.8.7
     R04751  Hexanoyl-CoA + FAD <=> trans-Hex-2-enoyl-CoA + FADH2
    1.3.8.8
     R04751  Hexanoyl-CoA + FAD <=> trans-Hex-2-enoyl-CoA + FADH2
   1.3.99  With unknown physiological acceptors
    1.3.99.-
     R04751  Hexanoyl-CoA + FAD <=> trans-Hex-2-enoyl-CoA + FADH2
IUBMB reaction hierarchy [BR:br08202]
 1. Oxidoreductase reactions
  1.3.8.1
   R01178  Short-chain acyl-CoA <=> Electron-transferring flavoprotein
    R04751  Hexanoyl-CoA <=> FAD
  1.3.8.7
   R00392  Acyl-CoA <=> Electron-transferring flavoprotein
    R04751  Hexanoyl-CoA <=> FAD
  1.3.8.8
   R00392  Acyl-CoA <=> Electron-transferring flavoprotein
    R04751  Hexanoyl-CoA <=> FAD
Orthology
K00232  acyl-CoA oxidase [EC:1.3.3.6]
K00248  butyryl-CoA dehydrogenase [EC:1.3.8.1]
K00249  acyl-CoA dehydrogenase [EC:1.3.8.7]
K00255  long-chain-acyl-CoA dehydrogenase [EC:1.3.8.8]
K06445  acyl-CoA dehydrogenase [EC:1.3.99.-]
K09478  short-chain 2-methylacyl-CoA dehydrogenase [EC:1.3.8.5]
Reference
1  [PMID:12057976]
  Authors
Campbell JW, Cronan JE Jr.
  Title
The enigmatic Escherichia coli fadE gene is yafH.
  Journal
J Bacteriol 184:3759-64 (2002)
DOI:10.1128/JB.184.13.3759-3764.2002
Other DBs
RHEA: 31210

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