KEGG   REACTION: R04758
Entry
R04758                      Reaction                               
Name
11beta-hydroxyandrost-4-ene-3,17-dione:NADP+ 11-oxidoreductase
Definition
11beta-Hydroxyandrost-4-ene-3,17-dione + NADP+ <=> Adrenosterone + NADPH + H+
Equation
C05284 + C00006 <=> C05285 + C00005 + C00080
Reaction class
RC00001  C00005_C00006
RC00154  C05284_C05285
Enzyme
1.1.1.146
Pathway
rn00140  Steroid hormone biosynthesis
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.146
     R04758  11beta-Hydroxyandrost-4-ene-3,17-dione + NADP+ <=> Adrenosterone + NADPH + H+
IUBMB reaction hierarchy [BR:br08202]
 1. Oxidoreductase reactions
  1.1.1.146
   R03203  11beta-Hydroxysteroid <=> 11-Oxosteroid
    R04758  11beta-Hydroxyandrost-4-ene-3,17-dione <=> Adrenosterone
Orthology
K15680  corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:1.1.1.146]

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