KEGG   REACTION: R05068Help
Entry
R05068                      Reaction                               

Name
(R)-2,3-Dihydroxy-3-methylpentanoate:NADP+ oxidoreductase (isomerizing)
Definition
(R)-2,3-Dihydroxy-3-methylpentanoate + NADP+ <=> (R)-3-Hydroxy-3-methyl-2-oxopentanoate + NADPH + H+
Equation
Reaction class
RC00001  C00005_C00006
RC00726  C06007_C14463
Enzyme
Pathway
rn00290  Valine, leucine and isoleucine biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01130  Biosynthesis of antibiotics
rn01210  2-Oxocarboxylic acid metabolism
rn01230  Biosynthesis of amino acids
Module
M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
M00570  Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Orthology
K00053  ketol-acid reductoisomerase [EC:1.1.1.86]

DBGET integrated database retrieval system