KEGG   REACTION: R05329
Entry
R05329                      Reaction                               

Name
Spermidine:eIF5A-lysine 4-aminobutyltransferase (propane-1,3-diamine-forming)
Definition
[eIF5A-precursor]-lysine + Spermidine <=> [eIF5A-precursor]-deoxyhypusine + 1,3-Diaminopropane
Equation
Comment
multi-step reaction (see R07477+R07479+R07480+R07478)
Reaction class
RC00053  C00315_C00986  C07281_C07282
Enzyme
Other DBs
RHEA: 33302

KEGG   REACTION: R07477
Entry
R07477                      Reaction                               

Name
spermidine:NAD+ oxidoreductase
Definition
Spermidine + NAD+ <=> Dehydrospermidine + NADH + H+
Equation
Comment
the first step of multi-step reaction (see R05329, R07477+R07479+R07480+R07478)
subsequently R07479
Reaction class
RC00001  C00003_C00004
RC01819  C00315_C15853
Enzyme
Other DBs
RHEA: 19908

KEGG   REACTION: R07479
Entry
R07479                      Reaction                               

Name
dehydrospermidine:[enzyme]-lysine N-4-aminobutylidenetransferase
Definition
Dehydrospermidine + [eIF5A-precursor]-lysine <=> N-(4-Aminobutylidene)-[eIF5A-precursor]-lysine + 1,3-Diaminopropane
Equation
Comment
the second step of multi-step reaction (see R05329, R07477+R07479+R07480+R07478)
following after R07477
subsequently R07480
Reaction class
RC01859  C00986_C15853  C07281_C15854
Enzyme
Other DBs
RHEA: 52991

KEGG   REACTION: R07480
Entry
R07480                      Reaction                               

Name
N-(4-aminobutylidene)-[enzyme]-lysine:[eIF5A-precursor]-lysine N-4-aminobutylidenetransferase
Definition
N-(4-Aminobutylidene)-[eIF5A-precursor]-lysine + [eIF5A-precursor]-lysine <=> N-(4-Aminobutylidene)-[eIF5A-precursor]-lysine + [eIF5A-precursor]-lysine
Equation
Comment
the third step of multi-step reaction (see R05329, R07477+R07479+R07480+R07478)
following after R07479
subsequently R07478
Reaction class
RC01859  C07281_C15854
Enzyme
Other DBs
RHEA: 52995

KEGG   REACTION: R07478
Entry
R07478                      Reaction                               

Name
[eIF5A-precursor]-deoxyhypusine:NAD+ oxidoreductase
Definition
N-(4-Aminobutylidene)-[eIF5A-precursor]-lysine + NADH + H+ <=> [eIF5A-precursor]-deoxyhypusine + NAD+
Equation
Comment
the last step of multi-step reaction (see R05329, R07477+R07479+R07480+R07478)
following after R07480
Reaction class
RC00001  C00003_C00004
RC01819  C07282_C15854
Enzyme
Other DBs
RHEA: 52999

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