KEGG   REACTION: R05471Help
Entry
R05471                      Reaction                               

Name
clavulanate:NADP+ oxidoreductase
Definition
Clavulanate-9-aldehyde + NADPH + H+ <=> Clavulanic acid + NADP+
Equation
Comment
car, clavulanate-9-aldehyde reductase
cad, clavulanic acid dehydrogenase
Reaction class
RC00001  C00005_C00006
RC00649  C06661_C06662
Pathway
rn00331  Clavulanic acid biosynthesis
rn01100  Metabolic pathways
rn01130  Biosynthesis of antibiotics
Orthology
K12677  clavulanate-9-aldehyde reducatase
Reference
1  [PMID:9614345]
  Authors
McGowan SJ, Bycroft BW, Salmond GP.
  Title
Bacterial production of carbapenems and clavams: evolution of beta-lactam antibiotic pathways.
  Journal
Trends Microbiol 6:203-8 (1998)
DOI:10.1016/S0966-842X(98)01251-7
Other DBs
RHEA: 42071

DBGET integrated database retrieval system