| Entry |
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| Name |
S-adenosyl-L-methionine:erythromycin-D 3''-O-methyltransferase
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| Definition |
S-Adenosyl-L-methionine + Erythromycin D <=> S-Adenosyl-L-homocysteine + Erythromycin B
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| Equation |
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| Comment |
EryG: O-methyl transferase
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| Reaction class |
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| Enzyme |
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| Pathway |
| rn00522 | Biosynthesis of 12-, 14- and 16-membered macrolides |
| rn01110 | Biosynthesis of secondary metabolites |
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| Module |
| M00774 | Erythromycin biosynthesis, propanoyl-CoA + methylmalonyl-CoA => deoxyerythronolide B => erythromycin A/B |
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| Orthology |
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| Reference |
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| Authors |
Summers RG, Donadio S, Staver MJ, Wendt-Pienkowski E, Hutchinson CR, Katz L. |
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| Title |
Sequencing and mutagenesis of genes from the erythromycin biosynthetic gene cluster of Saccharopolyspora erythraea that are involved in L-mycarose and D-desosamine production. |
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| Journal |
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| Reference |
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| Authors |
Haydock SF, Dowson JA, Dhillon N, Roberts GA, Cortes J, Leadlay PF |
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| Title |
Cloning and sequence analysis of genes involved in erythromycin biosynthesis in Saccharopolyspora erythraea: sequence similarities between EryG and a family of S-adenosylmethionine-dependent methyltransferases. |
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| Journal |
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| Other DBs |
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