KEGG   REACTION: R05639
Entry
R05639                      Reaction                               
Name
4,4-dimethyl-5a-cholesta-8,24-dien-3b-ol:NADP+ D14-oxidoreductase
Definition
14-Demethyllanosterol + NADP+ <=> 4,4-Dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + NADPH + H+
Equation
C05108 + C00006 <=> C11455 + C00005 + C00080
Reaction class
RC00001  C00005_C00006
RC01441  C05108_C11455
Enzyme
1.3.1.70
Pathway
rn00100  Steroid biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00101  Cholesterol biosynthesis, FPP => cholesterol
M00102  Ergocalciferol biosynthesis, FPP => ergosterol/ergocalciferol
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.70
     R05639  14-Demethyllanosterol + NADP+ <=> 4,4-Dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + NADPH + H+
Orthology
K00222  Delta14-sterol reductase [EC:1.3.1.70]
K19532  Delta14-sterol reductase (lamin-B receptor) [EC:1.3.1.70]
Other DBs
RHEA: 18564

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