KEGG   REACTION: R05640
Entry
R05640                      Reaction                               

Name
lanosterol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (14-methyl cleaving)
Definition
Lanosterol + 3 [Reduced NADPH---hemoprotein reductase] + 3 Oxygen <=> 4,4-Dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + Formate + 3 [Oxidized NADPH---hemoprotein reductase] + 4 H2O
Equation
C01724 + 3 C03024 + 3 C00007 <=> C11455 + C00058 + 3 C03161 + 4 C00001
Reaction class
RC01442  C01724_C11455
Enzyme
Pathway
rn00100  Steroid biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00101  Cholesterol biosynthesis, squalene 2,3-epoxide => cholesterol
M00102  Ergocalciferol biosynthesis, squalene 2,3-epoxide => ergosterol/ergocalciferol
Orthology
K05917  sterol 14alpha-demethylase [EC:1.14.14.154 1.14.15.36]
Other DBs
RHEA: 25289

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