KEGG   REACTION: R05815
Entry
R05815                      Reaction                               
Name
cobyrinate:L-glutamine amido-ligase (ADP-forming)
Definition
Cobyrinate + 2 L-Glutamine + 2 ATP + 2 H2O <=> Cob(II)yrinate a,c diamide + 2 L-Glutamate + 2 ADP + 2 Orthophosphate
Equation
C05773 + 2 C00064 + 2 C00002 + 2 C00001 <=> C06504 + 2 C00025 + 2 C00008 + 2 C00009
Comment
two-step reaction (see R09598+R09599)
Reaction class
RC00002  C00002_C00008
RC00010  C00025_C00064
RC01301  C05773_C06504
Enzyme
6.3.5.11
Pathway
rn00860  Porphyrin metabolism
rn01100  Metabolic pathways
rn01240  Biosynthesis of cofactors
Module
M00924  Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide
Brite
Enzymatic reactions [BR:br08201]
 6. Ligase reactions
  6.3  Forming carbon-nitrogen bonds
   6.3.5  Carbon-nitrogen ligases with glutamine as amido-N-donor
    6.3.5.11
     R05815  Cobyrinate + 2 L-Glutamine + 2 ATP + 2 H2O <=> Cob(II)yrinate a,c diamide + 2 L-Glutamate + 2 ADP + 2 Orthophosphate
Orthology
K02224  cobyrinic acid a,c-diamide synthase [EC:6.3.5.9 6.3.5.11]
Other DBs
RHEA: 26292

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Ontology (1)   
   KEGG BRITE (1)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG RCLASS (3)   
Gene (3841)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (3840)   
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KEGG   REACTION: R09598
Entry
R09598                      Reaction                               
Definition
Cobyrinate + L-Glutamine + ATP + H2O <=> Cobyrinate c-monamide + L-Glutamate + ADP + Orthophosphate
Equation
C05773 + C00064 + C00002 + C00001 <=> C19724 + C00025 + C00008 + C00009
Comment
first step of two-step reaction (see R05815, R09598+R09599)
Reaction class
RC00002  C00002_C00008
RC00010  C00025_C00064  C05773_C19724
Enzyme
6.3.5.11
Brite
Enzymatic reactions [BR:br08201]
 6. Ligase reactions
  6.3  Forming carbon-nitrogen bonds
   6.3.5  Carbon-nitrogen ligases with glutamine as amido-N-donor
    6.3.5.11
     R09598  Cobyrinate + L-Glutamine + ATP + H2O <=> Cobyrinate c-monamide + L-Glutamate + ADP + Orthophosphate
Other DBs
RHEA: 34550

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Ontology (1)   
   KEGG BRITE (1)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG RCLASS (2)   
All databases (12)   

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KEGG   REACTION: R09599
Entry
R09599                      Reaction                               
Definition
Cobyrinate c-monamide + L-Glutamine + ATP + H2O <=> Cob(II)yrinate a,c diamide + L-Glutamate + ADP + Orthophosphate
Equation
C19724 + C00064 + C00002 + C00001 <=> C06504 + C00025 + C00008 + C00009
Comment
second step of two-step reaction (see R05815, R09598+R09599)
Reaction class
RC00002  C00002_C00008
RC00010  C00025_C00064  C06504_C19724
Enzyme
6.3.5.11
Brite
Enzymatic reactions [BR:br08201]
 6. Ligase reactions
  6.3  Forming carbon-nitrogen bonds
   6.3.5  Carbon-nitrogen ligases with glutamine as amido-N-donor
    6.3.5.11
     R09599  Cobyrinate c-monamide + L-Glutamine + ATP + H2O <=> Cob(II)yrinate a,c diamide + L-Glutamate + ADP + Orthophosphate
Other DBs
RHEA: 34554

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG RCLASS (2)   
All databases (12)   

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