KEGG   REACTION: R06295
Entry
R06295                      Reaction                               
Name
ent-kaur-16-en-19-oate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (hydroxylating)
Definition
ent-7alpha-Hydroxykaur-16-en-19-oic acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Gibberellin A12 aldehyde + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Equation
C11875 + C03024 + C00007 <=> C06093 + C03161 + 2 C00001
Comment
the second step of three-step reaction (see R10067, R06294+R06295+R06297)
Reaction class
RC01622  C06093_C11875
Enzyme
1.14.14.107
Pathway
rn00904  Diterpenoid biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00927  Gibberellin A12 biosynthesis, GAPP => GA12
M00929  Gibberellin A1 biosynthesis, GGPP => GA1
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.107
     R06295  ent-7alpha-Hydroxykaur-16-en-19-oic acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Gibberellin A12 aldehyde + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Orthology
K04123  ent-kaurenoic acid monooxygenase [EC:1.14.14.107]
K12917  cytochrome P450 monooxygenase 1
Other DBs
RHEA: 22907

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Ontology (1)   
   KEGG BRITE (1)   
Pathway (8)   
   KEGG PATHWAY (6)   
   KEGG MODULE (2)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG RCLASS (1)   
Gene (457)   
   KEGG ORTHOLOGY (2)   
   KEGG GENES (455)   
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