KEGG   REACTION: R06449
Entry
R06449                      Reaction                               
Definition
5-O-beta-D-Mycaminosyltylactone + 2 NADPH + 2 Oxygen + 2 H+ <=> 20-Oxo-5-O-beta-mycaminosyltylactone + 2 NADP+ + 3 H2O
Equation
C12001 + 2 C00005 + 2 C00007 + 2 C00080 <=> C20760 + 2 C00006 + 3 C00001
Comment
cytochrome P450,TylI
multi-step reaction
Reaction class
RC00001  C00005_C00006
RC03223  C12001_C20760
Pathway
rn00522  Biosynthesis of 12-, 14- and 16-membered macrolides
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00773  Tylosin biosynthesis, methylmalonyl-CoA + malonyl-CoA => tylactone => tylosin
Orthology
K15992  cytochrome P450 TylI

  All links  
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (2)   
   KEGG RCLASS (2)   
Gene (2)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
All databases (18)   

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