KEGG   REACTION: R06454Help
Entry
R06454                      Reaction                               

Definition
8,8a-Deoxyoleandolide + 2 NADPH + 2 H+ + 2 Oxygen <=> Oleandolide + 2 NADP+ + 3 H2O
Equation
C11989 + 2 C00005 + 2 C00080 + 2 C00007 <=> C11990 + 2 C00006 + 3 C00001
Comment
cytochrome P450 monooxygenase,OleP
Reaction class
RC00001  C00005_C00006
RC01524  C11989_C11990
Pathway
rn00522  Biosynthesis of 12-, 14- and 16-membered macrolides
rn01100  Metabolic pathways
rn01130  Biosynthesis of antibiotics
Module
M00775  Oleandomycin biosynthesis, malonyl-CoA + methylmalonyl-CoA => 8,8a-deoxyoleandolide => oleandomycin
Orthology
K16008  cytochrome P450 monooxygenase OleP

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