KEGG   REACTION: R06568
Entry
R06568                      Reaction                               
Name
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing, reducing)
Definition
p-Coumaroyl-CoA + 3 Malonyl-CoA + NADPH + H+ <=> Isoliquiritigenin + 4 CoA + 3 CO2 + NADP+ + H2O
Equation
C00223 + 3 C00083 + C00005 + C00080 <=> C08650 + 4 C00010 + 3 C00011 + C00006 + C00001
Reaction class
RC00001  C00005_C00006
RC00004  C00010_C00083  C00010_C00223
RC02726  C00223_C08650
Enzyme
2.3.1.170
Pathway
rn00941  Flavonoid biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00940  Flavanone biosynthesis, p-coumaroyl-CoA => liquiritigenin
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.170
     R06568  p-Coumaroyl-CoA + 3 Malonyl-CoA + NADPH + H+ <=> Isoliquiritigenin + 4 CoA + 3 CO2 + NADP+ + H2O
Orthology
K00660  chalcone synthase [EC:2.3.1.74]
K08243  chalcone reductase
Other DBs
RHEA: 10587

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