KEGG   REACTION: R06777Help
Entry
R06777                      Reaction                               

Definition
3-Methylpyrrole-2,4-dicarboxylic acid + 3-Amino-4,7-dihydroxycoumarin + ATP <=> 5-[[(4,7-Dihydroxy-2-oxo-2H-1-benzopyran-3-yl)amino]carbonyl]-4-methyl-1H-pyrrole-3-carboxylate + AMP + Diphosphate
Equation
Comment
ligase, CouL
Reaction class
RC00162  C12477_C20637
RC00416  C12468_C20637
Pathway
rn00401  Novobiocin biosynthesis
rn01130  Biosynthesis of antibiotics
Orthology
K12709  8-demethylnovobiocic acid synthase [EC:6.3.1.15]

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