KEGG   REACTION: R07204
Entry
R07204                      Reaction                               
Name
5beta-cholestane-3alpha,7alpha-diol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (12alpha-hydroxylating)
Definition
3alpha,7alpha-Dihydroxy-5beta-cholestane + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestane + [Oxidized NADPH---hemoprotein reductase] + H2O
Equation
C05452 + C03024 + C00007 <=> C05454 + C03161 + C00001
Reaction class
RC01218  C05452_C05454
Enzyme
1.14.14.139
Pathway
rn00120  Primary bile acid biosynthesis
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.139
     R07204  3alpha,7alpha-Dihydroxy-5beta-cholestane + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestane + [Oxidized NADPH---hemoprotein reductase] + H2O
Orthology
K07431  sterol 12-alpha-hydroxylase [EC:1.14.14.139]
Other DBs
RHEA: 15264

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Ontology (1)   
   KEGG BRITE (1)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG RCLASS (1)   
Gene (580)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (579)   
All databases (593)   

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