KEGG   REACTION: R07213
Entry
R07213                      Reaction                               
Name
L-tryptophan,tetrahydrobiopterin:oxygen oxidoreductase(5-hydroxylating)
Definition
L-Tryptophan + Tetrahydrobiopterin + Oxygen <=> 5-Hydroxy-L-tryptophan + 4a-Hydroxytetrahydrobiopterin
Equation
C00078 + C00272 + C00007 <=> C00643 + C15522
Reaction class
RC00490  C00078_C00643
Enzyme
1.14.16.4
Pathway
rn00790  Folate biosynthesis
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.16  With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.16.4
     R07213  L-Tryptophan + Tetrahydrobiopterin + Oxygen <=> 5-Hydroxy-L-tryptophan + 4a-Hydroxytetrahydrobiopterin
Orthology
K00502  tryptophan 5-monooxygenase [EC:1.14.16.4]
Other DBs
RHEA: 16712

  All links  
Chemical reaction (1)   
   SABIO-RK (1)   
All databases (1)   

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