KEGG   REACTION: R07233
Entry
R07233                      Reaction                               
Name
S-adenosyl-L-methionine:rRNA (guanine-N1-)-methyltransferase
Definition
S-Adenosyl-L-methionine + rRNA <=> S-Adenosyl-L-homocysteine + rRNA containing N1-methylguanine
Equation
C00019 + C00240 <=> C00021 + C04152
Comment
general reaction
The enzyme ec 2.1.1.187 specifically methylates guanine745 at N1 in 23S rRNA.
The enzyme ec 2.1.1.188 specifically methylates guanine748 at N1 in 23S rRNA.
Reaction class
RC00003  C00019_C00021
Enzyme
2.1.1.187       2.1.1.188
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.187
     R07233  S-Adenosyl-L-methionine + rRNA <=> S-Adenosyl-L-homocysteine + rRNA containing N1-methylguanine
    2.1.1.188
     R07233  S-Adenosyl-L-methionine + rRNA <=> S-Adenosyl-L-homocysteine + rRNA containing N1-methylguanine
Orthology
K00563  23S rRNA (guanine745-N1)-methyltransferase [EC:2.1.1.187]
K14336  23S rRNA (guanine748-N1)-methyltransferase [EC:2.1.1.188]
Other DBs
RHEA: 42903 42907

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