| Entry |
|
|---|
| Name |
acyl-CoA:malonyl-CoA C-acyltransferase (dihydromonacolin L-[acp]-forming)
|
|---|
| Definition |
9 Malonyl-CoA + 11 NADPH + 10 H+ + S-Adenosyl-L-methionine + Acyl-carrier protein <=> Dihydromonacolin L-[acyl-carrier protein] + 9 CoA + 9 CO2 + 11 NADP+ + S-Adenosyl-L-homocysteine + 6 H2O
|
|---|
| Equation |
|
|---|
|
 |
|---|
| Comment |
multi-step reaction
Acy-carrier protein is acp domain of LOVB [KO: K20981].
|
|---|
| Reaction class |
|
|---|
| Enzyme |
|
|---|
| Pathway |
| rn00997 | Biosynthesis of various other secondary metabolites |
| rn01110 | Biosynthesis of secondary metabolites |
|
|---|
| Module |
| M00893 | Lovastatin biosynthesis, malonyl-CoA => lovastatin acid |
|
|---|
| Brite |
Enzymatic reactions [BR:br08201]
2. Transferase reactions
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.161
R07251 9 Malonyl-CoA + 11 NADPH + 10 H+ + S-Adenosyl-L-methionine + Acyl-carrier protein <=> Dihydromonacolin L-[acyl-carrier protein] + 9 CoA + 9 CO2 + 11 NADP+ + S-Adenosyl-L-homocysteine + 6 H2O
|
|---|
| Orthology |
|
|---|
| Other DBs |
|
|---|
