KEGG   REACTION: R07985
Entry
R07985                      Reaction                               
Name
(S)-2-hydroxymethylglutarate:NAD+ oxidoreductase
Definition
2-Formylglutarate + NADH + H+ <=> (S)-2-(Hydroxymethyl)glutarate + NAD+
Equation
C16159 + C00004 + C00080 <=> C16390 + C00003
Reaction class
RC00001  C00003_C00004
RC00099  C16159_C16390
Enzyme
1.1.1.291
Pathway
rn00760  Nicotinate and nicotinamide metabolism
rn01120  Microbial metabolism in diverse environments
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.291
     R07985  2-Formylglutarate + NADH + H+ <=> (S)-2-(Hydroxymethyl)glutarate + NAD+
Orthology
K19647  2-hydroxymethylglutarate dehydrogenase [EC:1.1.1.291]
Reference
1  [PMID:16894175]
  Authors
Alhapel A, Darley DJ, Wagener N, Eckel E, Elsner N, Pierik AJ.
  Title
Molecular and functional analysis of nicotinate catabolism in Eubacterium barkeri.
  Journal
Proc Natl Acad Sci U S A 103:12341-6 (2006)
DOI:10.1073/pnas.0601635103
Other DBs
RHEA: 15508

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