KEGG   REACTION: R08255Help
Entry
R08255                      Reaction                               

Definition
Irinotecan + H2O <=> SN-38 + 1,4'-Bipiperidine-1'-carboxylic acid
Equation
Comment
carboxylesterase
Reaction class
RC00475  C16641_C16836
RC00476  C11173_C16641
Enzyme
Pathway
rn00983  Drug metabolism - other enzymes
Orthology
K01044  carboxylesterase 1 [EC:3.1.1.1]
K03927  carboxylesterase 2 [EC:3.1.1.1 3.1.1.84 3.1.1.56]

DBGET integrated database retrieval system