KEGG   REACTION: R08549Help
Entry
R08549                      Reaction                               

Name
2-Oxoglutarate dehydrogenase complex
Definition
2-Oxoglutarate + CoA + NAD+ <=> Succinyl-CoA + CO2 + NADH + H+
Equation
Comment
multi-step reaction (see R01700+R02570+R07618)
Reaction class
RC00001  C00003_C00004
RC00004  C00010_C00091
RC02833  C00026_C00091
Enzyme
1.2.4.2         1.8.1.4         2.3.1.61
Pathway
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01130  Biosynthesis of antibiotics
rn01200  Carbon metabolism
Orthology
K00164  2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]
K00382  dihydrolipoamide dehydrogenase [EC:1.8.1.4]
K00658  2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]
Other DBs
RHEA: 27789

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