KEGG   REACTION: R08615
Entry
R08615                      Reaction                               
Name
UDP-glucuronate glucuronohydrolase
Definition
UDP-glucuronate + H2O <=> UDP + D-Glucuronate
Equation
C00167 + C00001 <=> C00015 + C00191
Reaction class
RC00005  C00015_C00167
RC00078  C00167_C00191
Enzyme
2.4.1.17
Pathway
rn00053  Ascorbate and aldarate metabolism
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.17
     R08615  UDP-glucuronate + H2O <=> UDP + D-Glucuronate
IUBMB reaction hierarchy [BR:br08202]
 2. Transferase reactions
  2.4.1.17
   R09428  Acceptor <=> Acceptor beta-D-glucuronoside
    R08615  H2O <=> D-Glucuronate
Orthology
K00699  glucuronosyltransferase [EC:2.4.1.17]
Reference
1  [PMID:17222174]
  Authors
Linster CL, Van Schaftingen E
  Title
Vitamin C. Biosynthesis, recycling and degradation in mammals.
  Journal
FEBS J 274:1-22 (2007)
DOI:10.1111/j.1742-4658.2006.05607.x
Reference
2  [PMID:16689937]
  Authors
Linster CL, Van Schaftingen E.
  Title
Glucuronate, the precursor of vitamin C, is directly formed from UDP-glucuronate in liver.
  Journal
FEBS J 273:1516-27 (2006)
DOI:10.1111/j.1742-4658.2006.05172.x
Other DBs
RHEA: 26076

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG RCLASS (2)   
Gene (7405)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (7404)   
All databases (7418)   

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