KEGG   REACTION: R08764Help
Entry
R08764                      Reaction                               

Name
6-hydroxynicotinate,NADH:oxygen oxidoreductase (3-hydroxylating, decarboxylating)
Definition
6-Hydroxynicotinate + NADH + Oxygen + H+ <=> 2,5-Dihydroxypyridine + NAD+ + CO2 + H2O
Equation
Reaction class
RC00001  C00003_C00004
RC00115  C01020_C01059
Enzyme
Pathway
rn00760  Nicotinate and nicotinamide metabolism
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
Module
M00622  Nicotinate degradation, nicotinate => fumarate
Orthology
K14974  6-hydroxynicotinate 3-monooxygenase [EC:1.14.13.114]
Reference
1  [PMID:10091591]
  Authors
Nakano H, Wieser M, Hurh B, Kawai T, Yoshida T, Yamane T, Nagasawa T.
  Title
Purification, characterization and gene cloning of 6-hydroxynicotinate 3-monooxygenase from Pseudomonas fluorescens TN5.
  Journal
Eur J Biochem 260:120-6 (1999)
DOI:10.1046/j.1432-1327.1999.00124.x
Other DBs
RHEA: 27336

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